In this seven-lesson unit, students develop an understanding of molecular biology through an exploration of viral and antibody testing used for detecting SARS-CoV-2 infections, which causes the disease known as COVID-19. Students explore patient case studies to make a diagnosis and further recommendations for their care. Students also learn about and discuss health inequities and bioethical issues related to the COVID-19 pandemic. The unit incorporates opportunities for engaging with productive uncertainty, developing scientific argumentation practices, and considering bioethical implications of scientific discoveries and policy decisions.

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This unit includes two wet labs. In the Molecular Testing lesson, students will conduct a wet lab using gel electrophoresis to examine a patient sample to determine if they are positive, negative, or inconclusive for COVID-19 infection. In the Antibody Testing lesson, students will conduct a second wet lab, running an indirect ELISA to see if their patient has had an infection with SARS-CoV-2 in the past.

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All lesson plans include suggested adaptations for virtual learning settings, including alternate activities for the two wet labs.

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Lessons Plans and Supporting Materials

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Cover sheet – Word Document  PDF

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To access the COVID-19 Testing & Inequities curriculum (lesson plans, student handouts, slide decks), see this webpage from Fred Hutchinson Cancer Research Center: COVID-19 Testing and Inequities.